Clinical Trials
Explore Arvinas-Sponsored Clinical Trials
Find trials that may be relevant for you and your patients.
Arvinas Development Program
Explore our development pipeline of PROTAC® protein degraders.
Enrolling Oncology Clinical Trials
Learn more about our enrolling clinical trials.
The agents listed below are currently under investigation. Their safety and effectiveness have not yet been established.
Vepdegestrant
VERITAC-2
Vepdegestrant vs fulvestrant in previously treated ER+/HER- advanced or metastatic breast cancer
VERITAC-3
Vepdegestrant plus palbociclib vs letrozole plus palbociclib in previously untreated ER+/HER- advanced breast cancer
TACTIVE-U
An umbrella study of vepdegestrant plus other anticancer therapies in ER+ advanced or metastatic breast cancer
TACTIVE-K
A phase 1b/2 open-label study of vepdegestrant (ARV-471) in combination with PF-07220060 (a CDK4 inhibitor) in patients with ER+/HER2- advanced or metastatic breast cancer
ARV-766
ARV-766-mCRPC-101
ARV-766 alone or in combination with abiraterone in previously treated metastatic prostate cancer
ARV-766 is out-licensed to Novartis
ARV-393
ARV-393-101
ARV-393 in adult patients with advanced non-Hodgkin lymphoma
Prostate Cancer
A phase 1/2 open-label study of ARV-766 in patients with metastatic castration-resistant prostate cancer and progression on prior systemic therapies