Clinical Trials
Explore Arvinas-Sponsored Clinical Trials
Find trials that may be relevant for you and your patients.
Arvinas Development Program
Explore our development pipeline of PROTAC® protein degraders.
Enrolling Oncology Clinical Trials
Learn more about our enrolling clinical trials.
The agents listed below are currently under investigation. Their safety and effectiveness have not yet been established.
Vepdegestrant
VERITAC-2
A phase 3, randomized, open-label study of vepdegestrant (ARV-471) vs fulvestrant in patients with ER+/HER2- advanced breast cancer
VERITAC-3
A phase 3, randomized, open-label, study of vepgedestrant (ARV-471) plus palbociclib vs letrozole plus palbociclib in patients with ER+/HER2- advanced breast cancer
TACTIVE-U
A phase 1b/2 umbrella study of vepdegestrant (ARV-471) in combination with other anticancer treatments in patients with ER+ advanced or metastatic breast cancer
TACTIVE-K
A phase 1b/2 open-label study of vepdegestrant (ARV-471) in combination with PF-07220060 (a CDK4 inhibitor) in patients with ER+/HER2- advanced or metastatic breast cancer
ARV-766
A phase 1/2 open-label study of ARV-766 in patients with metastatic castration-resistant prostate cancer and progression on prior systemic therapies
ARV-393
ARV-393-101
A phase 1 first-in-human, open-label, dose-escalation study of ARV-393 in adult patients with advanced non-Hodgkin lymphoma
Prostate Cancer
A phase 1/2 open-label study of ARV-766 in patients with metastatic castration-resistant prostate cancer and progression on prior systemic therapies